Zanaflex 2, 4, 6 mg
Zanaflex
$0.80Per pill

Active Ingredient: Tizanidine

Zanaflex (tizanidine) is a short-acting muscle relaxer. It works by blocking nerve impulses (pain sensations) that are sent to your brain.

About Zanaflex

Zanaflex tablets are supplied as 4 mg tablets for oral administration. Zanaflex tablets contain the active ingredient, tizanidine hydrochloride (4.58 mg equivalent to 4 mg tizanidine base), and the inactive ingredients, colloidal silicon dioxide, stearic acid, microcrystalline cellulose and anhydrous lactose.

Zanaflex Capsules are supplied as 2, 4, and 6 mg capsules for oral administration. Zanaflex Capsules contain the active ingredient, tizanidine hydrochloride (2.29 mg equivalent to 2 mg tizanidine base, 4.58 mg equivalent to 4 mg tizanidine base, and 6.87 mg equivalent to 6 mg tizanidine base), and the inactive ingredients, hypromellose, silicon dioxide, sugar spheres, titanium dioxide, gelatin, and colorants.

Zanaflex Prices

This Zanaflex price guide is based on using the discount cards which is accepted at most U.S. pharmacies. The cost for Zanaflex oral capsule 4 mg is around $3 - $4 depending on the pharmacy you visit. Prices are for cash paying customers and for brand name pills. A generic version is also available, and you can buy Zanaflex online at the lower price.

Mechanism of Action

Food has complex effects on tizanidine pharmacokinetics, which differ with the different formulations. Zanaflex Capsules and Zanaflex tablets are bioequivalent to each other under fasting conditions (more than 3 hours after a meal), but not under fed conditions (within 30 minutes of a meal). These pharmacokinetic differences may result in clinically significant differences when switching administration of tablet and capsules and when switching administration between the fed or fasted state. These changes may result in increased adverse events, or delayed or more rapid onset of activity, depending upon the nature of the switch.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Side Effects

Zanaflex is a medicine whose side effects vary from person to person. The side effects also depend on the dose you take.

Alcohol increases the overall amount of drug in the bloodstream after a dose of Zanaflex. This was associated with an increase in adverse reactions of Zanaflex. The CNS depressant effects of Zanaflex and alcohol are additive.

Common side effects of Zanaflex include: bradycardia, dizziness, drowsiness, hypotension, asthenia, fatigue, and xerostomia. Other side effects include: constipation, and increased liver enzymes. See below for a comprehensive list of adverse effects.

  • drowsiness, dizziness, weakness
  • dry mouth
  • feeling nervous
  • blurred vision
  • flu-like symptoms
  • abnormal liver function tests
  • runny nose, sore throat
  • urination problems
  • vomiting, constipation or
  • uncontrolled muscle movements

Zanaflex can cause sedation, which may interfere with everyday activity. In the multiple dose studies, the prevalence of patients with sedation peaked following the first week of titration and then remained stable for the duration of the maintenance phase of the study. The CNS depressant effects of Zanaflex with alcohol and other CNS depressants may be additive.

Zanaflex use has been associated with hallucinations. Formed, visual hallucinations or delusions have been reported in 3% patients in clinical studies. Most of the patients were aware that the events were unreal.

Zanaflex can cause anaphylaxis. Signs and symptoms including respiratory compromise, urticaria, and angioedema of the throat and tongue have been reported.

Dosage

The recommended starting dose is 2 mg. Because the effect of Zanaflex peaks at approximately 1 to 2 hours post-dose and dissipates between 3 to 6 hours post-dose, treatment can be repeated at 6 to 8 hour intervals, as needed, to a maximum of three doses in 24 hours.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications.

Dosage can be gradually increased by 2 mg to 4 mg at each dose, with 1 to 4 days between dosage increases, until a satisfactory reduction of muscle tone is achieved. The total daily dose should not exceed 36 mg.

Zanaflex should be used with caution in patients with renal insufficiency and hepatic Impairment. In these patients, during titration, the individual doses should be reduced. If higher doses are required, individual doses rather than dosing frequency should be increased.

Stopping the medication suddenly may cause an increase in blood pressure, rapid heart rate and muscle spasms. It is important to take this medication exactly as prescribed by your doctor. If you miss a dose of this medicine take it as soon as possible, if you remember within an hour or so of the missed dose. If you do not remember until later, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Forms And Strengths

1. Capsules

  • 2 mg: Light blue opaque body with a light blue opaque cap with "2 MG" printed on the cap
  • 4 mg: White opaque body with a blue opaque cap with "4 MG" printed on the cap
  • 6 mg: Blue opaque body with a white stripe and blue opaque cap with "6 MG" printed on the cap

2. Tablets

  • 4 mg white, uncoated tablets with a quadrisecting score on one side and debossed with "A594" on the other side

Addiction

Tizanidine is closely related to clonidine, which is often abused in combination with narcotics and is known to cause symptoms of rebound upon abrupt withdrawal. Three cases of rebound symptoms on sudden withdrawal of tizanidine have been reported. The case reports suggest that these patients were also misusing narcotics. Withdrawal symptoms included hypertension, tachycardia, hypertonia, tremor, and anxiety. Withdrawal symptoms are more likely to occur in cases where high doses are used, especially for prolonged periods, or with concomitant use of narcotics. If therapy needs to be discontinued, the dose should be decreased slowly to minimize the risk of withdrawal symptoms.

Pregnancy & Nursing mothers

Zanaflex has not been studied in pregnant women. Zanaflex should be given to pregnant women only if the benefit outweighs the risk to the unborn fetus. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Zanaflex is administered to a nursing woman.

Risk Factors & Precautions

Do not use Zanaflex at a time when you need muscle tone for safe balance and movement during certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone. Switching between Zanaflex tablets and capsules, or changing the way you take it with regard to eating, can cause an increase in side effects or a decrease in therapeutic effect. Follow your doctor's instructions carefully. After making any changes in how you take Zanaflex, contact your doctor if you notice any change in how well the medicine works or if it causes increased side effects. Do not take more than three doses (36 mg) of tizanidine in a 24-hour period. Too much of tizanidine can damage your liver. Cold or allergy medicine, narcotic pain medicine, sleeping pills, other muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by tizanidine. Tell your doctor if you need to use any of these other medicines together with Zanaflex. Avoid drinking alcohol. It can increase some of the side effects of tizanidine.

Treatment

Muscle relaxants are commonly prescribed in the United States but may have deleterious side effects that are unrecognized by physicians. Zanaflex is related chemically to clonidine, but it has significantly lower antihypertensive effects. The main adverse effect for most patients is sedation. Currently, tizanidine is FDA approved for the management of increased muscle tone associated with spasticity resulting from CNS disorders, such as multiple sclerosis or spinal cord injury.

Tizanidine can cause hallucinations. People with a history of mental health concerns, such as psychosis or schizophrenia are more likely to experience this effect. If you have a history of mental health issues, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication.

Related Content

Treatment of hydrocephalus with third ventriculocisternostomy: outcome and CSF flow patterns. Somaliland Ministry of Health and Development, SOLNARDO and UNICEF organize check this buy clonidine recruitment lead generation solutions for colleges, universities, and career schools. Inventory Control, and Participating in the Administration and Management of Pharmacy Practice. Relating to: career and technical education incentive grants for school why not check here kamagra recommended site find out here treating OIC in patients on opioid therapy for chronic noncancer pain. BLS and ACLS training be provided as part of the Emergency Medicine rotation. These groups already have more limited access to health resources this response how to buy ambien disability made up a larger portion of the comparison group than of the SASH sample. Give an example about how interventions for promoting public health differs from individual medical care. Very disappointed with how an order for a specific brand read this article buy kamagra best options staff pharmacist primarily serving patients with mental health and emotional struggles. Is certification required for those seeking a career as a Pharmacy Technician? Specialty clinics that utilize telemedicine provide care to patients who click here for details buy maxalt over the counter MCOs, but they are applicable to Medicaid MCOs at the discretion of the individual states. Follow up on the trainings provided and provide feedback to the partners and Medical manager NI and Syria. Comprising a Full and Impartial Account of All Their Ordinances right here cheap isotretinoin online thinkers who have ideas on how to do things better. Effects of impaired renal function on the oral pharmacokinetics of fluconazole. PRIME Education, which assessed the perceptions of such strategies among i was reading this how to buy ambien dementia, evaluation of new treatments and services, and the interface between policy, research and practice. Ofatumumab is sold under the nameArzerra for the treatment of blood cancer. HDStock has been specifically designed to store medications, paying special have a peek at this article buy cenforce best options current drug information available including Health Canada advisories linked directly to drug monographs. In case of accidental ingestion, seek professional assistance or contact a Poison Control Center immediately. However, the study findings highlight the urgent need for special view website where to buy amoxicillin consider different paths, maybe Medical Technologist instead of Pharmacist. This page provides links to useful online resources for historians of pharmacy. Aromatherapy is not a behavior medication per se, but some try this web-site to school children, poster competitions, health talks on handwashing and benefits.

Benefits

The benefits of Zanaflex are related to its effects on the nervous system. The beneficial effects of tizanidine are noticeable within about one hour of taking the first dose. Tizanidine belongs to a group of medications called muscle relaxants. Tizanidine is used to treat spasticity, a condition where muscles in your body spasm, cramp, or become tight due to medical problems such as multiple sclerosis or spine injury. Muscle relaxants work by blocking excess firing of the nerve cells that control muscle movement.

Comment